Histamine research

26795851 – histamine

Histamine headache
This enabler is not often thought of. Therefore, this is the form that often comes to us.

Histamine is indispensable to the human body because it performs many vital functions. It is produced by the body but also absorbed in variable amounts with the diet. Problems arise only in the case of excessive (excessive) concentrations of histamine or undegraded histamine.

Histamine intolerance is caused by a (temporary) deficiency or inhibition of the enzyme diamine oxidase (DAO). DAO is the enzyme responsible for the breakdown of histamine. Although DAO is found throughout the body, the gut harbors the most important and active site of action. The enzymatic activity of DAO determines the degradation rate of histamine. If a DAO deficiency/inhibition (inhibition) is present, the organism cannot break down histamine absorbed through food or released from body cells quickly enough, and a histamine intolerance exists.

The test for measuring a most genetic defect of the histamine-degrading enzyme (DAO) diamine oxidase.

Histamine is also found in foods. A genetic mutation of the histamine-degrading diamine oxidase (DAO) and histamine N-methyltransferase (HMNT) enzymes can lead to lower than normal activity so that histamine accumulates in the body and causes allergy-like symptoms. This is known as Histamine intolerance.See further treatment histamine intolerance

Other forms of headaches:

The headache that is by far the most common is a migraine or tension headache. Both are treatable and very common. Treatment should be focused by type of headache.

Tension headache

This is by far the most common form of headache. Even though people claim to have migraines, these headaches originate from the muscles in the neck, especially the trapezius pars descendens and the sternocleidomastoid (for those who love anatomy) . You can then find trigger points or tender points in those muscles that attach to the skull rim , just slightly to the left and right of the occipital hole continuing behind the ear. These points connect to points on the skull and forehead and or behind the eyes. When these muscles are tight they pull, as it were, on the membrane that lies over the skull, irritating that membrane in such a way that a headache results.

Usually several factors play a role in the development of headaches: sleep, hormones, immunology( defenses) nutrition and exercise.


Migraines cause intense pain, usually on one side of the head. Often there is an aura, visual disturbances or flashes of light observed.

Once a migraine occurs, people also often experience nausea, sweating, dizziness, sometimes even speech disorders, and sensitivity to light and sound. A very occasional loss of strength in an arm or leg.

Migraines often last for days, unlike tension headache which you usually get rid of after a good night’s sleep.

In the past, migraines were often thought to be a vascular problem, which would narrow and dilate vessels. Others assumed that migraines arose from a deficiency in the neurotransmitter serotonin. Serotonin controls sleep and mood but also does something to the blood vessels.

Personally, I think it is a combination of a number of underlying causes, including nutritional deficiencies, allergies or intolerances to food and hormonal imbalances.

Medication-dependent headaches

Some migraine sufferers rely so heavily on painkillers, making this When people frequently reach for a painkiller, they may end up with a headache. It is a frequent headache that often lasts a whole day.

Certain medications can trigger this image. Consider paracethamol and aspirin, the NSAId group ( ibuprofen diclofenac) anti migraine medication, Beta blockers and ACE inhibitors, some antibiotics and caffeine-containing foods.It is not wise to just stop your medication. However, you can begin to address the cause naturally and gradually reduce medication.

Cluster headache

This form of headache that is felt in sudden attacks is relatively rare. It is a unilateral headache, that is, on one side of the head. Often this happens just at night.Something may be visible about an eye redness or watering, a narrowed pupil, a closed nose or just a runny nose. People are sometimes anxious, irritated and tired


Hormonal headaches
We also see this type of headache often. Regular medication does not always help and the pill is often not the solution either. Fortunately, there is quite a bit you can do about it. One of the tests we use is the urine estrogen detox test.

Headache trigger; your boss
More specifically, work stress can cause tension headaches or even a major migraine. The exact cause is still unknown, but scientists suspect it has to do with hypersensitive nerve pathways in the brain. Stress produces increased muscle tension, which in itself is a headache trigger.

Posture and muscle use bound headaches
Raised shoulders, an office chair with insufficient support for the back, a computer screen that is not adjusted to the correct height or the phone wedged between head and shoulder: poor (work) posture causes tension headaches. A breathing pattern that is too high often plays into this. So if you have frequent headaches, it is wise to take a look at your posture. Also consider your standing posture, your couch hanging posture and your sports posture. For this you can go to complimed who has more than 25 years of experience in this field and combines it with orthomolecular techniques. Too much muscle tension of the jaw muscle the m. masseter can cause headaches. Teeth grinding also has this effect.

Caffeine can provide relief from headaches. It’s even in painkillers. But too much of it can induce headaches. Or too variable use of coffee ( sleeping in on the weekends and thus not taking coffee) can also give headaches. And when you are a true coffee addict, if you cut back, the symptoms will only worsen at first.




Contact Complimed to schedule an appointment.